EHTG and Collaborative Research Studies

International collaboration can improve the quality and success of research into inherited cancer syndromes by increasing recruitment and by the sharing of ideas and expertise. A major aim of EHTG is to promote such collaborative studies.

At EHTG’s symposia, researchers can present their proposals and studies at an early stage and establish the collaborations that will facilitate success.

Members can advertise their studies on the EHTG website. Doing so helps development of collaborations online with our multidisciplinary membership. There is a strong track record of success in collaborative research through EHTG (see details of example publications on this website).

Collaborative Studies that are currently recruiting

• Patients with #10q23 deletions
• Role of MCM8/9 variants in (colorectal) cancer predisposition
• The Prospective Lynch Syndrome Database – PLSD (Other sub-studies are active within PLSD e.g. Osteosarcoma in Lynch Syndrome[JS2] )
• European Database Constitutional Mismatch Repair Syndrome: C4CMMRD
• Prospective study of duodenal adenomas and cancer in MAP
• De novo MMR mutations in Lynch Syndrome
• New Juvenile Polyposis Genes.
  Contacts ian.tomlinson@igmm.ed.ac.uk or karl.heinimann@usb.ch » Details
• CAPP3 – clinical trial of aspirin chemprevention in Lynch Syndrome

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Proposals for Collaborative Studies

• Identification of predictors of CRC development in MMR mutation carriers under colonoscopy surveillance Proposal (PDF)
• Role of Genetic Modifiers in Disease Risk – Lynch Syndrome Proposal (PowerPoint)
• DiagMMR assay validation (Functional Lynch syndrome carrier testing from skin) Proposal (PowerPoint)
• Can CHRPE Be Used To Diagnose New Cases of Familial Adenomatous Polyposis? (Word)
• International Collaboration on MUTYH Proposal (PowerPoint)
• Osteosarcoma as part of the most common hereditary cancer syndrome, Lynch Syndrome. Mev Dominguez Valentin

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See Publications >

Contact Information

European Hereditary Tumour Group
Secretary:
Gabriele Sponholz

+49 (0)160 84 59 502
gs007@ehtg.org